Description

3β,11β,21-Tris(Trimethylsiloxy)-5α-Pregnan-20-One o-Methyl Oxime is a high-purity, organosilicon-modified steroid derivative, primarily utilized as a key synthetic intermediate in advanced pharmaceutical research and development. Its value lies in its functionalized structure, which provides a versatile scaffold for the synthesis of more complex bioactive molecules, particularly in the field of steroid chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries who require reliable, high-quality building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Steroid Chemistry Research: Used in academic and industrial R&D for exploring new synthetic pathways and modifying steroid core structures to alter biological activity.
• Process Development: Serves as a reference standard or starting material for scaling up and optimizing manufacturing processes for target molecules.
• Biochemical Probe Development: Potential use in creating labeled or modified compounds for studying steroid hormone receptors and metabolic pathways.

Basic Information

Item	Details
Product Name	3β,11β,21-Tris(Trimethylsiloxy)-5α-Pregnan-20-One o-Methyl Oxime
CAS No.	57325-78-7
Molecular Formula	C30H57NO4Si3
Molecular Weight	580.03 g/mol
Synonyms	5α-Pregnan-20-one, 3,11,21-tris[(trimethylsilyl)oxy]-, O-methyloxime; 3β,11β,21-Tris-O-(trimethylsilyl)-5α-pregnan-20-one O-methyloxime; Tris(trimethylsilyl) ether derivative of 5α-pregnan-20-one O-methyloxime; Steroid TMS derivative; 57325-78-7; Pregnane TMS oxime derivative
EINECS	Contact for details

Quality Control

Our 3β,11β,21-Tris(Trimethylsiloxy)-5α-Pregnan-20-One o-Methyl Oxime is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to prevent degradation upon exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.