Description

(5'β,1S)-2,2-Dimethyl-4'β-Nitrospiro[Cyclopentane-1,6'-[1]Azabicyclo[3.3.0]Octane] is a high-purity, structurally complex spirocyclic organic compound featuring a nitro group and an azabicyclo[3.3.0]octane core. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a key chiral intermediate or building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents with specific stereochemical configurations.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of complex drug candidates, especially those targeting neurological or cardiovascular pathways.
• Agrochemical Research: Used in the development of new pesticides or herbicides where its unique spirocyclic structure may confer specific biological activity.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to construct molecules with high enantiomeric purity.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring precise stereochemistry.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(5'β,1S)-2,2-Dimethyl-4'β-Nitrospiro[Cyclopentane-1,6'-[1]Azabicyclo[3.3.0]Octane]
CAS No.	57308-84-6
Molecular Formula	C13H20N2O2
Molecular Weight	236.31 g/mol
Synonyms	(1S,5'R)-2,2-Dimethyl-4'-nitro-1-azaspiro[bicyclo[3.3.0]octane-6,1'-cyclopentane]; 4'-Nitro-2,2-dimethylspiro[cyclopentane-1,6'-[1]azabicyclo[3.3.0]octane]; Spiro[cyclopentane-1,6'-[1]azabicyclo[3.3.0]octane], 2,2-dimethyl-4'-nitro-, (1S,5'R)-rel-; (1S,5'R)-2,2-Dimethyl-4'-nitrospiro[cyclopentane-1,6'-1-azabicyclo[3.3.0]octane]; Nitrospiroazabicyclooctane derivative
EINECS	Contact for details

Quality Control

Our (5'β,1S)-2,2-Dimethyl-4'β-Nitrospiro[Cyclopentane-1,6'-[1]Azabicyclo[3.3.0]Octane] is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.