Description

3α,17-Bis(Trimethylsiloxy)-5β-Pregnan-20-One o-Methyl Oxime is a high-purity, synthetic steroid derivative primarily used as a key pharmaceutical intermediate. This compound is critical for research and development in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is essential for manufacturers and R&D laboratories in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise and reliable building blocks for advanced steroid chemistry.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of steroidal drugs and hormones.
• Research & Development: Used in academic and industrial laboratories for exploring new synthetic pathways and novel steroid analogs.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Fine Chemical Synthesis: Employed in the production of specialized, high-value steroid compounds for various applications.

Basic Information

Product Name	3α,17-Bis(Trimethylsiloxy)-5β-Pregnan-20-One o-Methyl Oxime
CAS No.	57305-32-5
Molecular Formula	C₂₉H₅₃NO₃Si₂
Molecular Weight	519.91 g/mol
Synonyms	5β-Pregnan-3α,17-diol-20-one 3,17-bis(trimethylsilyl) ether oxime; 3α,17β-Bis(trimethylsiloxy)-5β-pregnan-20-one O-methyloxime; 20-Oximino-5β-pregnane-3α,17α-diol 3,17-bis(trimethylsilyl) ether; Pregnane-3α,17α-diol-20-one bis(trimethylsilyl) ether oxime; 57305-32-5; 3α,17α-Bis(trimethylsiloxy)-5β-pregnan-20-one O-methyloxime
EINECS	Contact for details

Quality Control

Our 3α,17-Bis(Trimethylsiloxy)-5β-Pregnan-20-One o-Methyl Oxime is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.