Description

3α,17-Bis(Trimethylsiloxy)-5β-Androst-16-Ene is a high-purity, organosilicon-protected steroid derivative, specifically designed for advanced pharmaceutical and research applications. This compound serves as a critical synthetic intermediate, offering enhanced stability and reactivity for the production of specialized steroid-based molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents and complex chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroid-based active pharmaceutical ingredients (APIs) and drug candidates.
• Research & Development: Used in academic and industrial R&D for studying steroid metabolism, receptor interactions, and developing new synthetic pathways.
• Hormone Analog Synthesis: Serves as a precursor for the preparation of modified androstane derivatives with potential biological activity.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in steroid analysis.
• Process Chemistry: Utilized in scale-up and process optimization for the commercial manufacturing of complex steroid molecules.

Basic Information

Product Name	3α,17-Bis(Trimethylsiloxy)-5β-Androst-16-Ene
CAS No.	57305-19-8
Molecular Formula	C25H46O2Si2
Molecular Weight	434.81 g/mol
Synonyms	5β-Androst-16-en-3α,17-diyl bis(trimethylsilyl) ether; 3α,17-Bis-O-(trimethylsilyl)-5β-androst-16-ene; Androst-16-ene-3α,17-diol, bis(trimethylsilyl) ether; 3α,17-Bis(trimethylsilyloxy)-5β-androst-16-ene; 5β-Androst-16-en-3α,17-diol bis(trimethylsilyl) ether; 16-Androstene-3α,17-diol, bis(trimethylsilyl) ether; 3α,17-Bis(TMS)-5β-androst-16-ene
EINECS	Contact for details

Quality Control

Our 3α,17-Bis(Trimethylsiloxy)-5β-Androst-16-Ene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.