Description

3α,11β-Bis(Trimethylsiloxy)-5β-Androstan-17-One o-Benzyl Oxime is a high-purity, advanced pharmaceutical intermediate featuring a steroidal backbone with specific silyl ether and oxime protecting groups. This compound is critical for the synthesis of complex steroid derivatives, offering precise control over molecular structure and reactivity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the exploration of new steroid receptor modulators and hormone analogs.
• Process Chemistry: Serves as a protected intermediate in scalable manufacturing processes for high-value fine chemicals.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: Utilized in studies investigating steroid metabolism, enzyme inhibition, and biochemical pathways.

Basic Information

Product Name	3α,11β-Bis(Trimethylsiloxy)-5β-Androstan-17-One o-Benzyl Oxime
CAS No.	57305-17-6
Molecular Formula	C32H53NO3Si2
Molecular Weight	555.94 g/mol
Synonyms	5β-Androstan-17-one, 3,11-bis[(trimethylsilyl)oxy]-, O-(phenylmethyl)oxime; 3α,11β-Bis(trimethylsiloxy)-5β-androstan-17-one O-benzyl oxime; 17-(Benzyloxyimino)-3α,11β-bis(trimethylsiloxy)-5β-androstane; Androstane-17-one O-benzyl oxime derivative; Steroid silyl ether oxime; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3α,11β-Bis(Trimethylsiloxy)-5β-Androstan-17-One o-Benzyl Oxime is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.