Description

3α-(Trimethylsiloxy)-5α-Androstan-17-One o-Benzyl Oxime is a high-purity, advanced pharmaceutical intermediate with the CAS number 57305-13-2. This compound is a critical building block in the synthesis of complex steroid-based active pharmaceutical ingredients (APIs), offering precise structural control for downstream reactions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of steroidal drugs and hormone analogs.
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new chemical entities targeting hormone receptors.
• Process Chemistry: Serves as a standard or reference material in scaling up API manufacturing processes.
• Biochemical Research: Employed in studies investigating steroid metabolism, enzyme inhibition, and receptor binding assays.

Basic Information

Product Name	3α-(Trimethylsiloxy)-5α-Androstan-17-One o-Benzyl Oxime
CAS No.	57305-13-2
Molecular Formula	C29H45NO2Si
Molecular Weight	467.77 g/mol
Synonyms	3α-(Trimethylsilyloxy)-5α-androstan-17-one O-benzyl oxime; 5α-Androstan-17-one, 3-[(trimethylsilyl)oxy]-, O-(phenylmethyl)oxime; 3α-(Trimethylsiloxy)-5α-androstan-17-one O-benzyloxime; Androstane oxime derivative; Steroid silyl ether oxime; 57305-13-2; 3-TMS-androstanone benzyl oxime
EINECS	Contact for details

Quality Control

Our 3α-(Trimethylsiloxy)-5α-Androstan-17-One o-Benzyl Oxime is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.