Description

3α-(Trimethylsiloxy)-5α-Androst-9(11)-En-17-One is a high-purity steroidal intermediate of significant importance in pharmaceutical synthesis. This compound is valued for its role as a versatile building block in the production of advanced active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and advanced organic synthesis sectors for developing therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of steroidal drugs and hormones.
• Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and novel chemical entities.
• API Manufacturing: Serves as a critical precursor in the commercial-scale production of specific active pharmaceutical ingredients.
• Fine Chemical Synthesis: Employed in the preparation of complex, high-value specialty chemicals and reference standards.

Basic Information

Product Name	3α-(Trimethylsiloxy)-5α-Androst-9(11)-En-17-One
CAS No.	57305-04-1
Molecular Formula	C22H36O2Si
Molecular Weight	360.61 g/mol
Synonyms	3α-(Trimethylsilyloxy)-5α-androst-9(11)-en-17-one; 5α-Androst-9(11)-en-17-one, 3α-(trimethylsilyloxy)-; 3α-Trimethylsiloxy-5α-androst-9(11)-en-17-one; 3α-TMS-5α-androst-9(11)-en-17-one; Androst-9(11)-en-17-one, 3α-(trimethylsilyloxy)-, (5α)-; 3α-Hydroxy-5α-androst-9(11)-en-17-one trimethylsilyl ether; 3α-TMS-androst-9(11)-en-17-one
EINECS	Contact for details

Quality Control

Our 3α-(Trimethylsiloxy)-5α-Androst-9(11)-En-17-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.