Description

5-[3-Chloro-2-(Trimethylsiloxy)Propyl]-1,3-Dimethyl-5-Phenyl-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized organosilicon-modified barbiturate derivative, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in its unique molecular architecture, which combines a reactive chloropropyl group with a trimethylsilyl-protected alcohol, enabling precise functionalization in complex synthesis pathways. This compound is primarily needed by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), fine chemicals, and advanced material science projects.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex drug candidates, particularly those requiring barbiturate or pyrimidinetrione core structures.
• Organic Synthesis Reagent: Used in advanced organic reactions, including nucleophilic substitutions and coupling reactions, where its silyl ether group acts as a protective moiety.
• Chemical Research & Development: Serves as a model compound or starting material in academic and industrial R&D for exploring new synthetic methodologies and reaction mechanisms.
• Fine Chemical Production: Employed in the manufacture of high-value, low-volume specialty chemicals for the agrochemical and material science industries.
• Protecting Group Chemistry: The trimethylsiloxy group can be utilized in synthetic strategies to protect alcohol functionalities during complex molecular assembly.

Basic Information

Product Name	5-[3-Chloro-2-(Trimethylsiloxy)Propyl]-1,3-Dimethyl-5-Phenyl-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	57305-01-8
Molecular Formula	C18H25ClN2O4Si
Molecular Weight	396.94 g/mol
Synonyms	1,3-Dimethyl-5-phenyl-5-[3-chloro-2-(trimethylsiloxy)propyl]barbituric acid; 5-[3-Chloro-2-(trimethylsilyloxy)propyl]-1,3-dimethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione; 1,3-Dimethyl-5-phenyl-5-(3-chloro-2-trimethylsiloxypropyl)barbituric acid; 5-(3-Chloro-2-trimethylsiloxypropyl)-1,3-dimethyl-5-phenylbarbituric acid; Barbituric acid derivative, 5-[3-chloro-2-(trimethylsiloxy)propyl]-1,3-dimethyl-5-phenyl-; CAS 57305-01-8
EINECS	Contact for details

Quality Control

Our 5-[3-Chloro-2-(Trimethylsiloxy)Propyl]-1,3-Dimethyl-5-Phenyl-2,4,6(1H,3H,5H)-Pyrimidinetrione is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.