Description

2,5-Dioxo-Bicyclo[2.2.2]Octane-1,4-Dicarboxylic Acid Dimethyl Ester is a high-purity, functionalized bicyclic compound that serves as a critical advanced intermediate in sophisticated organic synthesis. Its rigid, multi-functional structure makes it a valuable building block for creating complex molecular architectures with precise stereochemistry. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors who require reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those requiring rigid, polycyclic frameworks.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides where the bicyclo[2.2.2]octane core imparts stability and bioactivity.
• Polymer & Material Science: Monomer or cross-linking agent for producing high-performance polymers with enhanced thermal and mechanical properties.
• Ligand & Catalyst Development: Starting material for synthesizing chelating ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, pigments, and other specialty organic compounds.
• Academic & Industrial R&D: Versatile scaffold for methodological development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	2,5-Dioxo-Bicyclo[2.2.2]Octane-1,4-Dicarboxylic Acid Dimethyl Ester
CAS No.	57293-62-6
Molecular Formula	C12H14O6
Molecular Weight	254.24 g/mol
Synonyms	Dimethyl 2,5-Dioxobicyclo[2.2.2]octane-1,4-dicarboxylate; 1,4-Bis(methoxycarbonyl)bicyclo[2.2.2]octane-2,5-dione; Bicyclo[2.2.2]octane-1,4-dicarboxylic acid, 2,5-dioxo-, dimethyl ester; Dimethyl Bicyclo[2.2.2]octane-1,4-dicarboxylate-2,5-dione
EINECS	Contact for details

Quality Control

Our 2,5-Dioxo-Bicyclo[2.2.2]Octane-1,4-Dicarboxylic Acid Dimethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.