Description

(2S)-4'Aβ,5',6',7',8',8'A-Hexahydro-2',5',5',8'Aα-Tetramethylspiro[Benzofuran-2(3H),1'(4'H)-Naphthalen]-5-Ol is a high-purity, complex spirocyclic compound with a defined stereochemistry. This compound is valued for its unique molecular architecture, which serves as a critical chiral building block and intermediate in advanced organic synthesis. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents.
• Asymmetric Synthesis: Utilized as a sophisticated building block for constructing complex, stereochemically defined molecules.
• Fine Chemical Production: Serves as a precursor in the manufacture of high-value specialty chemicals and performance materials.
• Academic & Industrial Research: Used in methodological studies and process chemistry development due to its intricate spirocyclic structure.
• Fragrance & Flavor Chemistry: Potential intermediate for synthesizing novel aromatic compounds with specific olfactory properties.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specialized properties.

Basic Information

Product Name	(2S)-4'Aβ,5',6',7',8',8'A-Hexahydro-2',5',5',8'Aα-Tetramethylspiro[Benzofuran-2(3H),1'(4'H)-Naphthalen]-5-Ol
CAS No.	57291-89-1
Molecular Formula	C24H34O2
Molecular Weight	354.53 g/mol
Synonyms	(2S)-4'Aβ,5',6',7',8',8'A-Hexahydro-2',5',5',8'Aα-tetramethylspiro[benzofuran-2(3H),1'(4'H)-naphthalen]-5-ol; Ambrox; Ambroxide; (2S,4aR,5aS,8aS,8bR)-2,5,5,8a-Tetramethyl-1,2,3,4,4a,5,5a,6,7,8,8a,8b-dodecahydronaphtho[2,1-b]furan-2-ol; (2S,4aR,5aS,8aS,8bR)-Dodecahydro-2,5,5,8a-tetramethylnaphtho[2,1-b]furan-2-ol; (2S)-Ambrox; (-)-Ambrox; (S)-(-)-Ambroxide
EINECS	Contact for details

Quality Control

Our (2S)-4'Aβ,5',6',7',8',8'A-Hexahydro-2',5',5',8'Aα-Tetramethylspiro[Benzofuran-2(3H),1'(4'H)-Naphthalen]-5-Ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.