Description

n-Acetyl-o-Formyl-L-Serine Methyl Ester is a specialized, high-purity amino acid derivative used as a critical building block in advanced organic synthesis. This compound is valued for its reactive formyl and acetyl-protected serine backbone, enabling precise chemical modifications. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, bioactive molecules, and complex organic intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis for introducing modified serine residues.
• Bioconjugation: Serves as a versatile linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating custom molecular libraries.
• Protecting Group Strategy: Utilized in multi-step organic syntheses where orthogonal protection of amino and hydroxyl groups is required.
• Agrochemical Synthesis: Potential intermediate in the development of specialized amino acid-derived crop protection agents.

Basic Information

Product Name	n-Acetyl-o-Formyl-L-Serine Methyl Ester
CAS No.	57289-21-1
Molecular Formula	C7H11NO5
Molecular Weight	189.17 g/mol
Synonyms	N-Acetyl-O-formyl-L-serine methyl ester; L-Serine, N-acetyl-O-formyl-, methyl ester; Methyl N-acetyl-O-formyl-L-serinate; Acetylformylserine Methyl Ester; (2S)-2-(Acetylamino)-3-formyloxypropanoic acid methyl ester; O-Formyl-N-acetyl-L-serine methyl ester; N-Acetyl-O-formylserine methyl ester
EINECS	Contact for details

Quality Control

Our n-Acetyl-o-Formyl-L-Serine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.