Description

Cyanine Dye 7 CAS NO 57282-58-3 is a near-infrared (NIR) fluorescent dye belonging to the cyanine family, characterized by its high molar absorptivity and emission in the far-red to NIR region. This compound is essential for advanced bioimaging and diagnostic applications due to its deep tissue penetration and minimal background autofluorescence. It is primarily needed by researchers and manufacturers in the biotechnology, pharmaceutical, and medical diagnostics sectors for applications such as fluorescence microscopy, in vivo imaging, and the development of optical sensors.

Application

• Fluorescence Microscopy & Bioimaging: Used as a fluorescent probe for labeling proteins, nucleic acids, and cellular structures in fixed and live-cell imaging.
• In Vivo Imaging: Employed in preclinical research for non-invasive deep-tissue imaging in animal models due to its near-infrared emission.
• Flow Cytometry: Serves as a detection reagent for cell sorting and analysis, often in conjunction with antibodies or other targeting molecules.
• Optical Sensor Development: Integrated into the design of chemical and biological sensors for detecting specific analytes.
• DNA/RNA Detection: Used in gel staining and quantitative assays like real-time PCR for nucleic acid quantification and visualization.
• Photodynamic Therapy (PDT) Research: Investigated as a potential photosensitizer agent in cancer treatment research.

Basic Information

Product Name	Cyanine Dye 7
CAS No.	57282-58-3
Molecular Formula	C37H47IN2O3S2
Molecular Weight	774.80 g/mol
Synonyms	Cy7; Cyanine 7; Sulfo-Cyanine7; 1H-Benz[e]indolium, 2-[2-[2-chloro-3-[(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-1,3,3-trimethyl-, iodide; IR-125; NIR Dye 7; Heptamethine cyanine dye; 2-[2-[2-Chloro-3-[(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-1,3,3-trimethyl-1H-benz[e]indolium iodide
EINECS	Contact for details

Quality Control

Our Cyanine Dye 7 is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment, NMR and mass spectrometry for structural confirmation, and spectrophotometry to verify optical properties. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing batch-specific results. Our quality system is designed to meet the stringent requirements of research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (or as indicated on the label). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Dark green to blue-green solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Absorption Maximum (λmax)	747 - 753 nm
Emission Maximum (λem)	773 - 779 nm
Extinction Coefficient (ε)	≥ 200,000 L·mol⁻¹·cm⁻¹
Moisture Content (KF)	≤ 5.0 %
Solubility	Soluble in DMSO, DMF, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.