Description

2,4-Dinitro-5-Fluorophenylazide is a specialized aromatic azide compound used as a key reagent in photoaffinity labeling and cross-linking studies. This compound matters for researchers and manufacturers requiring precise, light-activated covalent bonding to biological targets or materials. It is primarily needed by the pharmaceutical, biotechnology, and advanced materials sectors for probing molecular interactions, developing diagnostic tools, and creating functionalized polymers.

Application

• Photoaffinity Labeling: A critical reagent for covalently tagging proteins, enzymes, and receptors to study binding sites and biological pathways upon UV light activation.
• Bioconjugation & Cross-linking: Used to create stable cross-links between biomolecules for structural analysis, assay development, and stabilizing protein complexes.
• Polymer & Surface Modification: Employed to functionalize polymer chains or material surfaces with photo-reactive groups for creating smart materials and coatings.
• Proteomics Research: Facilitates the identification and characterization of low-abundance proteins and transient molecular interactions in complex biological samples.
• Chemical Biology Probe Development: Serves as a building block for synthesizing activity-based probes to visualize enzyme activity in live cells.
• Diagnostic Kit Manufacturing: Used in the development of diagnostic assays and kits that rely on specific, irreversible antibody-antigen binding.

Basic Information

Product Name	2,4-Dinitro-5-Fluorophenylazide
CAS No.	57258-58-9
Molecular Formula	C6H2FN5O4
Molecular Weight	227.11 g/mol
Synonyms	5-Fluoro-2,4-dinitrophenyl azide; 1-Azido-5-fluoro-2,4-dinitrobenzene; 2,4-Dinitro-5-fluorophenyl azide; DNPA-F; 5-Fluoro-2,4-dinitro-1-azidobenzene; (5-Fluoro-2,4-dinitrophenyl)azide; 2,4-Dinitro-5-fluoro-1-azidobenzene
EINECS	Contact for details

Quality Control

Our 2,4-Dinitro-5-Fluorophenylazide is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere such as argon or nitrogen for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.