Description

Cyclopropanecarboxylic Acid, 2-Cyano-1,2-Dimethyl-, Methyl Ester, trans- (9Ci) is a specialized, high-purity chemical intermediate characterized by its unique cyclopropane and cyano ester functional groups. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, offering precise stereochemistry and reactivity. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane ring contributes to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers and functional materials with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-Cyano-1,2-Dimethyl-, Methyl Ester, trans- (9Ci)
CAS No.	57234-25-0
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	trans-2-Cyano-1,2-dimethylcyclopropanecarboxylic acid methyl ester; Methyl trans-2-cyano-1,2-dimethylcyclopropanecarboxylate; (1R,2S)-rel-2-Cyano-1,2-dimethylcyclopropanecarboxylic Acid Methyl Ester; 2-Cyano-1,2-dimethylcyclopropanecarboxylic acid methyl ester, trans-; trans-2-Cyano-1,2-dimethylcyclopropane-1-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-Cyano-1,2-Dimethyl-, Methyl Ester, trans- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.