Description

Ethyl 5-Bromo-2-oxopentanoate is a versatile brominated ketoester building block of significant importance in advanced organic synthesis. Its value lies in its bifunctional reactivity, featuring both an electrophilic bromoalkyl group and a nucleophilic/electrophilic ketoester moiety, enabling the construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries, where it serves as a key precursor for heterocycles, active pharmaceutical ingredients (APIs), and other specialty intermediates.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of various drug candidates, particularly those containing pyrrolidine, piperidine, or other nitrogen-containing heterocyclic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that require specific halogenated side chains.
• Fine Chemical Production: Serves as a building block for specialty chemicals, flavors, fragrances, and advanced materials requiring precise molecular structures.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry, including studies on alkylation, cyclization, and cross-coupling reactions.
• Peptidomimetics: Employed in the synthesis of peptide analogs and constrained scaffolds for biomedical research.

Basic Information

Product Name	Ethyl 5-Bromo-2-oxopentanoate
CAS No.	57224-29-0
Molecular Formula	C7H11BrO3
Molecular Weight	223.07 g/mol
Synonyms	5-Bromo-2-oxopentanoic acid ethyl ester; Ethyl 5-bromo-2-oxovalerate; 2-Oxo-5-bromopentanoic acid ethyl ester; 5-Bromolevulinic acid ethyl ester; Ethyl 5-bromolevulinate; α-Keto-δ-bromovaleric acid ethyl ester; Ethyl α-keto-δ-bromovalerate; 57224-29-0
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-2-oxopentanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.