Description

1-[(4-Methylphenyl)Sulfonyl]-1,2,3,6-Tetrahydropyridine is a specialized sulfonamide derivative with a tetrahydropyridine scaffold, serving as a valuable synthetic intermediate in advanced organic chemistry. Its molecular architecture makes it a critical building block for constructing complex pharmacologically active molecules, offering precise control over molecular structure and properties. This compound is primarily sought by research institutions and pharmaceutical development companies engaged in medicinal chemistry, process R&D, and the synthesis of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Serves as a starting material for developing tool compounds and probes to study biological pathways and protein function.
• Agrochemical Synthesis: Potential intermediate in the research and development of novel crop protection agents and pesticides.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for fundamental organic synthesis and methodological studies.

Basic Information

Product Name	1-[(4-Methylphenyl)Sulfonyl]-1,2,3,6-Tetrahydropyridine
CAS No.	57186-75-1
Molecular Formula	C12H15NO2S
Molecular Weight	237.32 g/mol
Synonyms	1-(p-Toluenesulfonyl)-1,2,3,6-tetrahydropyridine; 1-(4-Methylbenzenesulfonyl)-1,2,3,6-tetrahydropyridine; 1-Tosyl-1,2,3,6-tetrahydropyridine; N-(p-Tolylsulfonyl)-1,2,3,6-tetrahydropyridine; 4-Methyl-N-(1,2,3,6-tetrahydropyridin-1-yl)benzenesulfonamide; 1,2,3,6-Tetrahydro-1-(p-tolylsulfonyl)pyridine; 57186-75-1
EINECS	Contact for details

Quality Control

Our production of 1-[(4-Methylphenyl)Sulfonyl]-1,2,3,6-Tetrahydropyridine adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. All materials are fully characterized and undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.