Description

1-Aza-Spiro[3.4]Octane is a high-value, nitrogen-containing spirocyclic building block of significant interest in modern synthetic chemistry. Its unique constrained bicyclic structure, featuring a spiro-fused azetidine ring, makes it a privileged scaffold for constructing complex three-dimensional molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use as a key intermediate in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of drug candidates targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its spirocyclic structure for enhanced bioactivity and selectivity.
• Chemical Biology & Probe Development: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways and protein function.
• Material Science Precursor: Potential use in the synthesis of specialized ligands for catalysis or as a monomer for advanced polymeric materials.
• Medicinal Chemistry SAR Studies: Employed to explore structure-activity relationships (SAR) by introducing conformational constraints into lead molecules.

Basic Information

Product Name	1-Aza-Spiro[3.4]Octane
CAS No.	57174-62-6
Molecular Formula	C7H13N
Molecular Weight	111.19 g/mol
Synonyms	1-Azaspiro[3.4]octane; Azaspiro[3.4]octane; 1-Aza-spiro[3.4]octane; Spiro[azetidine-3,1'-cyclopentane]; 1-Azoniabicyclo[3.1.0]hexane (cation form); 1-Aza-1-spiro[3.4]octane; 1-Aza-spiro(3,4)octane
EINECS	Contact for details

Quality Control

Our 1-Aza-Spiro[3.4]Octane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive R&D applications. We provide comprehensive analytical data, including HPLC purity, NMR, and MS confirmation. A Certificate of Analysis (COA) detailing all specifications is supplied with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.