Description

3-[(Trimethylsilyl)Oxy]Cholestane is a high-purity, steroidal organosilicon derivative, specifically a trimethylsilyl (TMS) ether of cholestane. This compound serves as a critical intermediate and analytical standard in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for applications such as derivatization for GC/MS analysis and as a building block for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: Acts as a key synthon in the multi-step synthesis of complex steroidal drugs and bioactive molecules.
• Analytical Reference Standard: Used for method development, calibration, and quantification in Gas Chromatography-Mass Spectrometry (GC/MS) analysis, particularly for sterol and steroid profiling.
• Derivatization Agent: Employed to enhance the volatility and thermal stability of hydroxyl-containing steroids for improved chromatographic separation and detection.
• Biochemical Research: Utilized in metabolic studies and as a probe to investigate enzyme mechanisms related to sterol biosynthesis and modification.
• Fine Chemical Synthesis: Serves as a protected form of cholestane for selective functionalization in the preparation of advanced materials and specialty chemicals.

Basic Information

Product Name	3-[(Trimethylsilyl)Oxy]Cholestane
CAS No.	56907-47-2
Molecular Formula	C₃₀H₅₄OSi
Molecular Weight	450.85 g/mol
Synonyms	Cholestane, 3-[(trimethylsilyl)oxy]-; 3-(Trimethylsiloxy)cholestane; 3-TMS-Cholestane; 3-O-Trimethylsilylcholestane; 3β-(Trimethylsilyloxy)cholestane; 3β-TMS-Cholestane; Cholestan-3β-yloxytrimethylsilane; (3β)-Cholestanyl Trimethylsilyl Ether
EINECS	Contact for details

Quality Control

Every batch of 3-[(Trimethylsilyl)Oxy]Cholestane is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles by HPLC/GC is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.