Description

Trimethyl[[17-(2-Propenyl)Estr-4-En-17β-Yl]Oxy]Silane is a high-purity, organosilicon-modified steroid derivative, serving as a critical advanced intermediate in pharmaceutical synthesis. Its core value lies in enabling precise chemical modifications for the development of novel therapeutic agents, offering researchers a versatile building block with enhanced stability and reactivity. This compound is essential for R&D and production teams in the pharmaceutical, biotechnology, and fine chemical sectors focused on steroid-based drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel steroid-based active pharmaceutical ingredients (APIs).
• Steroid Drug Discovery: Used in medicinal chemistry for the structural modification and derivatization of estrogen analogs to explore new biological activities.
• Process Chemistry Development: Employed in scaling up synthetic routes for complex steroid molecules, leveraging the silicon moiety for protective or directing group strategies.
• Biochemical Research: Serves as a probe or precursor in studying steroid hormone receptors and their signaling pathways.
• Fine Chemical Synthesis: Utilized in the preparation of specialized, high-value organosilicon compounds for advanced material and catalyst research.

Basic Information

Product Name	Trimethyl[[17-(2-Propenyl)Estr-4-En-17β-Yl]Oxy]Silane
CAS No.	56771-58-5
Molecular Formula	C24H38O2Si
Molecular Weight	386.65 g/mol
Synonyms	17β-[(Trimethylsilyl)oxy]-17-(2-propenyl)estr-4-ene; 17-Allyl-17β-(trimethylsilyloxy)estra-4-ene; Estra-4-en-17β-ol, 17-(2-propenyl)-, trimethylsilyl ether; 17-Allylestr-4-en-17β-ol trimethylsilyl ether; (17β)-17-(2-Propen-1-yl)-17-[(trimethylsilyl)oxy]estra-4-ene; Trimethylsilyl ether of 17-allyl-17β-hydroxyestra-4-ene
EINECS	Contact for details

Quality Control

Our Trimethyl[[17-(2-Propenyl)Estr-4-En-17β-Yl]Oxy]Silane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.