Description

3-Butynyl-1-Acetate is a versatile acetylated alkyne building block used in advanced organic synthesis. This compound is valued for its terminal alkyne functionality, which enables critical carbon-carbon bond-forming reactions like Sonogashira coupling and click chemistry. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Click Chemistry: An ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create triazole linkages.
• Organic Synthesis Building Block: Employed in Sonogashira, Glaser, and other palladium-catalyzed coupling reactions to introduce acetylene units.
• Liquid Crystal & OLED Research: Used in the synthesis of organic semiconductors and advanced display materials.

Basic Information

Product Name	3-Butynyl-1-Acetate
CAS No.	56703-55-0
Molecular Formula	C6H8O2
Molecular Weight	112.13 g/mol
Synonyms	3-Butyn-1-ol acetate; 3-Butynyl acetate; 4-Acetoxy-1-butyne; 1-Butyn-4-yl acetate; But-3-yn-1-yl acetate; 3-Butyn-1-yl ethanoate; 4-Acetoxybut-1-yne
EINECS	Contact for details

Quality Control

Our 3-Butynyl-1-Acetate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.420 - 1.430
Density (g/mL, 20°C)	0.95 - 0.98

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.