Description

3β-Trimethylsilyloxycholest-7-Ene is a high-purity, steroidal derivative featuring a trimethylsilyl (TMS) ether protecting group at the 3β-hydroxyl position. This compound serves as a crucial advanced synthetic intermediate in the research and development of novel steroid-based pharmaceuticals and bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex steroidal targets, where precise functional group manipulation is required.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroid-based drug candidates, including potential hormone modulators and anti-inflammatory agents.
• Research Chemical: Used in academic and industrial research to study steroid chemistry, reaction mechanisms, and the development of new synthetic methodologies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in chromatographic analysis (HPLC, GC) within fine chemical production.
• Biochemical Probe: Utilized in biochemical research to investigate sterol metabolism, enzyme interactions, and cellular signaling pathways related to cholesterol derivatives.
• Fine Chemical Synthesis: An intermediate for producing specialized steroidal compounds used in advanced materials science or as ligands in catalytic systems.

Basic Information

Item	Detail
Product Name	3β-Trimethylsilyloxycholest-7-Ene
CAS No.	56687-73-1
Molecular Formula	C₃₀H₅₂OSi
Molecular Weight	456.82 g/mol
Synonyms	Cholest-7-en-3β-ol, trimethylsilyl ether; 3β-[(Trimethylsilyl)oxy]cholest-7-ene; 3β-Trimethylsiloxycholest-7-ene; (3β)-3-[(Trimethylsilyl)oxy]cholest-7-ene; TMS-Cholest-7-en-3β-ol ether; 3β-TMS-Cholest-7-ene; 3β-Hydroxycholest-7-ene TMS ether; 3β-Trimethylsilylcholest-7-en-3-ol
EINECS	Contact for details

Quality Control

Our 3β-Trimethylsilyloxycholest-7-Ene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.