Description

Phosphorous Acid Methylbis(Trimethylsilyl) Ester is a specialized organosilicon reagent featuring a silyl-protected phosphite structure. This compound is a valuable intermediate in organic synthesis, offering a protected form of phosphorous acid for controlled reactivity. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring precise phosphorus introduction or as a silylating agent.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing phosphorus heterocycles or phosphate ester prodrugs.
• Agrochemical Synthesis: Serves as a key building block for creating organophosphorus pesticides, herbicides, and plant growth regulators.
• Ligand Precursor: Acts as a precursor for the preparation of phosphite and phosphonite ligands used in homogeneous catalysis, such as hydroformylation and hydrogenation.
• Silylating Agent: Employed to introduce trimethylsilyl (TMS) protecting groups onto sensitive hydroxyl or other protic functional groups in multi-step syntheses.
• Flame Retardant Synthon: Utilized in the research and development of new organophosphorus flame retardants for polymers and textiles.
• Material Science Research: Applied in the surface modification of inorganic materials or the synthesis of phosphorus-doped silicon-based precursors.

Basic Information

Item	Details
Product Name	Phosphorous Acid Methylbis(Trimethylsilyl) Ester
CAS No.	56666-36-5
Molecular Formula	C7H21O3PSi2
Molecular Weight	240.38 g/mol
Synonyms	Methylbis(trimethylsilyl) Phosphite; Methyl Phosphorodisilite, Bis(trimethylsilyl) Methyl Ester; Phosphorous Acid, Methyl Ester, Bis(trimethylsilyl) Ester; Bis(trimethylsilyl) Methyl Phosphite; (Methoxy)bis(trimethylsiloxy)phosphine; Methyl P,P-Bis(trimethylsilyl) Phosphonite
EINECS	Contact for details

Quality Control

Our Phosphorous Acid Methylbis(Trimethylsilyl) Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, GC, and HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.