Description

4-Methoxybenzyl Isocyanate is a versatile aromatic isocyanate building block essential for introducing the 4-methoxybenzyl (PMB) protecting group and constructing ureas and carbamates. Its reactivity makes it a critical intermediate for synthesizing advanced pharmaceutical compounds, agrochemicals, and specialty polymers. This high-purity chemical is primarily sought by R&D laboratories and production facilities in the life sciences and fine chemical sectors for its reliable performance in complex organic syntheses.

Application

• Key intermediate in the synthesis of pharmaceutical active ingredients (APIs) and agrochemicals.
• Building block for the preparation of urea and carbamate derivatives with biological activity.
• Reagent for introducing the 4-methoxybenzyl (PMB) protecting group for amines and alcohols in multi-step organic synthesis.
• Monomer or cross-linking agent in the production of specialty polyurethanes and polymers with tailored properties.
• Used in materials science research for surface modification and the creation of functional coatings.
• Starting material for the development of chemical probes and sensors in diagnostic applications.

Basic Information

Product Name	4-Methoxybenzyl Isocyanate
CAS No.	56651-60-6
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	p-Methoxybenzyl Isocyanate; (4-Methoxyphenyl)methyl Isocyanate; PMB-NCO; 4-Methoxybenzyl Isocyanat; 1-Isocyanatomethyl-4-methoxybenzene; 4-Methoxybenzylcarbylamine; Isocyanic Acid 4-Methoxybenzyl Ester
EINECS	Contact for details

Quality Control

Our 4-Methoxybenzyl Isocyanate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and our quality management system supports the needs of research and commercial-scale production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.