Description

2-[(Trimethylsilyl)Oxy]-1-([(Trimethylsilyl)Oxy]Methyl)Ethyl (9E)-9-Octadecenoate is a specialized organosilicon derivative of oleic acid, designed to provide enhanced stability and unique reactivity for advanced synthetic applications. This compound matters as a high-value intermediate, offering the lipophilic character of a fatty acid ester combined with the protective and silylating properties of trimethylsilyl (TMS) groups. It is primarily needed by R&D chemists and process developers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecules, modifying surfaces, or acting as a protected synthon.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) where the TMS-protected diol moiety and fatty acid chain introduce specific lipophilicity or act as a prodrug component.
• Agrochemical Synthesis: Serves as a key building block for creating novel surfactants, adjuvants, or active compounds with tailored release and penetration properties.
• Polymer Modification: Employed to functionalize polymers or resins, imparting hydrophobic characteristics, improving compatibility, or serving as a reactive site for further cross-linking.
• Surface Chemistry & Coatings: Acts as a silylating agent or a precursor for creating hydrophobic, low-surface-energy coatings on glass, metals, or ceramics.
• Organic Synthesis Reagent: Utilized as a protected diol equivalent or a source of the oleate anion under mild conditions for nucleophilic substitution reactions.
• Lubricant & Grease Additive: Functions as a high-performance additive in synthetic lubricants and greases, contributing to thermal stability and reducing friction.

Basic Information

Product Name	2-[(Trimethylsilyl)Oxy]-1-([(Trimethylsilyl)Oxy]Methyl)Ethyl (9E)-9-Octadecenoate
CAS No.	56554-42-8
Molecular Formula	C27H56O4Si2
Molecular Weight	500.90 g/mol
Synonyms	Bis(trimethylsilyl) Glycerol Monooleate; 1,3-Bis-O-(trimethylsilyl)glycerol 2-oleate; Glycerol 1,3-bis(trimethylsilyl) ether 2-oleate; Oleic Acid, 2,3-Bis[(trimethylsilyl)oxy]propyl Ester; (9E)-9-Octadecenoic Acid 2,3-Bis[(trimethylsilyl)oxy]propyl Ester; TMS-Protected Glycerol Monooleate; 2,3-Bis-O-TMS Glycerol-1-oleate
EINECS	Contact for details

Quality Control

Our 2-[(Trimethylsilyl)Oxy]-1-([(Trimethylsilyl)Oxy]Methyl)Ethyl (9E)-9-Octadecenoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the silyl ether groups. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.