Description

Methyl tert-Butylsulfinylacetate CAS NO 56535-32-1 is a specialized organosulfur compound that serves as a versatile chiral building block and reagent in advanced organic synthesis. Its value lies in its ability to introduce the tert-butylsulfinyl group, a highly effective chiral auxiliary for the stereoselective synthesis of complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where precise control over molecular stereochemistry is critical for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other therapeutics.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure pesticides and herbicides, where specific stereoisomers often exhibit superior biological activity.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for the synthesis of novel chiral sulfoxide ligands used in asymmetric catalysis, such as in transition metal-catalyzed reactions.
• Peptidomimetics Research: Employed in academic and industrial R&D for constructing non-natural amino acid derivatives and peptidomimetic scaffolds with defined stereocenters.
• Material Science: Investigated as a monomer or functional additive for creating specialty polymers with unique optical or electronic properties.

Basic Information

Product Name	Methyl tert-Butylsulfinylacetate
CAS No.	56535-32-1
Molecular Formula	C7H14O3S
Molecular Weight	178.25 g/mol
Synonyms	Acetic acid, 2-[(1,1-dimethylethyl)sulfinyl]-, methyl ester; Methyl 2-[(tert-butyl)sulfinyl]acetate; Methyl (tert-butylsulfinyl)acetate; tert-Butylsulfinylacetic acid methyl ester; 2-(tert-Butylsulfinyl)acetic acid methyl ester; Methyl 2-(tert-butylsulfinyl)acetate; (RS)-Methyl 2-(tert-butylsulfinyl)acetate
EINECS	Contact for details

Quality Control

Our Methyl tert-Butylsulfinylacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess (ee). We support cGMP-compliant production for pharmaceutical customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when dispensing from the original container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee (typical)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.