Description

Ethanone, 2-Bromo-1-(5-Methyl-3-Isoxazolyl)- is a specialized brominated heterocyclic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce functional complexity into target molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those containing the isoxazole pharmacophore for anti-inflammatory, antimicrobial, or CNS activity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the bromoacetyl group allows for further functionalization.
• Fine Chemical Building Block: Serves as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitutions for constructing complex organic frameworks.
• Material Science Research: Investigated as a monomer or functionalizing agent for creating specialized polymers with tailored properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new synthetic pathways in heterocyclic chemistry.

Basic Information

Product Name	Ethanone, 2-Bromo-1-(5-Methyl-3-Isoxazolyl)-
CAS No.	56400-88-5
Molecular Formula	C6H6BrNO2
Molecular Weight	204.02 g/mol
Synonyms	2-Bromo-1-(5-methyl-3-isoxazolyl)ethanone; 2-Bromo-1-(5-methylisoxazol-3-yl)ethan-1-one; 3-Acetyl-5-methylisoxazole, 2-bromo derivative; 2-Bromo-1-(5-methyl-1,2-oxazol-3-yl)ethanone; Bromo(5-methyl-3-isoxazolyl)methyl ketone; α-Bromo-5-methylisoxazole-3-acetophenone (obsolete); 56400-88-5; (5-Methyl-3-isoxazolyl)-2-bromoethanone
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Bromo-1-(5-Methyl-3-Isoxazolyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with batch-specific data are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.