Description

8-Phenyl-1,4-Dioxaspiro[4.5]Decane-8-Carbaldehyde is a specialized spirocyclic aldehyde building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a protected carbonyl and a phenyl-substituted spiro center, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its spirocyclic framework for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with tailored thermal and optical properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of complex aroma chemicals with unique olfactory profiles.

Basic Information

Item	Detail
Product Name	8-Phenyl-1,4-Dioxaspiro[4.5]Decane-8-Carbaldehyde
CAS No.	56327-24-3
Molecular Formula	C₁₇H₂₀O₃
Molecular Weight	272.34 g/mol
Synonyms	8-Phenyl-1,4-dioxaspiro[4.5]decane-8-carboxaldehyde; 8-Formyl-8-phenyl-1,4-dioxaspiro[4.5]decane; 8-Phenyl-1,4-dioxaspiro[4.5]decane-8-carbaldehyde; 8-Phenyl-8-formyl-1,4-dioxaspiro[4.5]decane; Phenylspiroacetaldehyde; 1,4-Dioxaspiro[4.5]decane-8-carbaldehyde, 8-phenyl-; 8-Phenylspiro[1,3-dioxolane-2,1'-cyclohexane]-8-carbaldehyde
EINECS	Contact for details

Quality Control

Our 8-Phenyl-1,4-Dioxaspiro[4.5]Decane-8-Carbaldehyde is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.