Description

4-(Trimethylsilyloxy)-α-Methyl-α-(Trimethylsilylamino)Benzenepropionic Acid Trimethylsilyl Ester is a highly functionalized, multi-silylated organic compound that serves as a critical protected intermediate in advanced synthetic chemistry. Its value lies in its ability to simultaneously protect reactive hydroxyl, amino, and carboxylic acid groups, enabling complex multi-step synthesis with high selectivity and yield. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules where precise functional group manipulation is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, especially those containing benzenepropionic acid derivatives.
• Peptide & Amino Acid Chemistry: Used as a protected derivative in the synthesis of non-proteinogenic amino acids and peptide analogs.
• Advanced Organic Synthesis: Serves as a versatile intermediate in multi-step total synthesis projects for natural products and complex heterocycles.
• Protecting Group Strategy: Employed in methodologies requiring the temporary protection of carboxylic acid, amine, and alcohol functionalities under anhydrous conditions.
• Material Science Research: Potential precursor for the development of novel silylated monomers or surface-modifying agents.
• Agrochemical Synthesis: Intermediate in the research and development of new crop protection agents with tailored properties.

Basic Information

Product Name	4-(Trimethylsilyloxy)-α-Methyl-α-(Trimethylsilylamino)Benzenepropionic Acid Trimethylsilyl Ester
CAS No.	56292-86-5
Molecular Formula	C21H41NO3Si3
Molecular Weight	463.81 g/mol
Synonyms	α-Methyl-α-(trimethylsilylamino)-4-(trimethylsilyloxy)benzenepropionic Acid Trimethylsilyl Ester; 4-(Trimethylsilyloxy)-α-methyl-α-[(trimethylsilyl)amino]benzenepropanoic Acid Trimethylsilyl Ester; Benzenepropanoic acid, 4-(trimethylsilyloxy)-α-methyl-α-[(trimethylsilyl)amino]-, trimethylsilyl ester; Tris(trimethylsilyl) Protected α-Amino Acid Derivative; TMS-Protected α-Methylphenylalanine Derivative
EINECS	Contact for details

Quality Control

Every batch of 4-(Trimethylsilyloxy)-α-Methyl-α-(Trimethylsilylamino)Benzenepropionic Acid Trimethylsilyl Ester is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical research and production needs. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and moisture content. Our quality commitment aligns with the standards expected in pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Handle and store in a well-ventilated area.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.