Description

1-O,3-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-2-[(Trimethylsilyl)Amino]-2-Deoxy-D-Glucitol is a fully silylated derivative of 2-amino-2-deoxy-D-glucitol, designed for advanced synthetic and analytical chemistry. This compound is a critical intermediate and derivatization agent, valued for its ability to enhance the volatility, stability, and detectability of complex carbohydrates and amino sugars in gas chromatography and mass spectrometry. It is primarily utilized by researchers and process chemists in pharmaceutical development, analytical laboratories, and specialty chemical synthesis.

Application

• Gas Chromatography (GC) and GC-MS Derivatization: Acts as a key reagent for the silylation of hydroxyl and amino groups in sugars and polyols, improving their thermal stability and chromatographic separation.
• Pharmaceutical Intermediate: Serves as a protected building block in the synthesis of complex glycosidase inhibitors, antiviral agents, and other bioactive carbohydrate-based molecules.
• Analytical Reference Standard: Used as a high-purity standard for method development and quantification in carbohydrate analysis.
• Glycobiology Research: Facilitates the study of carbohydrate structure and metabolism by enabling precise analysis of sugar alcohols and amino sugars.
• Specialty Chemical Synthesis: Employed in the preparation of sophisticated, functionalized organic compounds where selective protection and deprotection strategies are required.
• Mass Spectrometry Enhancement: Improves ionization efficiency and fragmentation patterns for clearer structural elucidation of polar analytes.

Basic Information

Product Name	1-O,3-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-2-[(Trimethylsilyl)Amino]-2-Deoxy-D-Glucitol
CAS No.	56282-41-8
Molecular Formula	C27H67NO6Si6
Molecular Weight	694.5 g/mol
Synonyms	2-Amino-2-deoxy-D-glucitol pentakis(trimethylsilyl) ether; 2-[(Trimethylsilyl)amino]-2-deoxy-D-glucitol pentakis(trimethylsilyl) ether; Hexakis(trimethylsilyl)-2-amino-2-deoxy-D-glucitol; Fully silylated 2-amino-2-deoxyglucitol; TMS derivative of 2-amino-2-deoxy-D-glucitol; Amino sugar alcohol TMS derivative; 2-Amino-2-deoxysorbitol hexa-TMS ether
EINECS	Contact for details

Quality Control

Our 1-O,3-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-2-[(Trimethylsilyl)Amino]-2-Deoxy-D-Glucitol is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR for identity and purity verification. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can compromise product integrity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.