Description

n-(2-Hydroxybenzoyl)Glycine Bis(Trimethylsilyl) Deriv. is a silylated derivative of salicyluric acid, primarily used as a key synthetic intermediate and protecting group reagent in advanced organic synthesis. This compound matters for its role in facilitating complex chemical transformations by protecting sensitive functional groups, particularly hydroxyl and carboxyl moieties, under demanding reaction conditions. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the production of active ingredients and novel molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a protected synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Peptide & Protein Chemistry: Acts as a protecting group reagent for carboxyl functionalities during solid-phase and solution-phase peptide synthesis.
• Organic Synthesis Reagent: Facilitates reactions requiring anhydrous conditions or protection of acid and phenol groups from undesired side reactions.
• Analytical Reference Standard: Employed as a high-purity standard in analytical methods (e.g., HPLC, GC-MS) for quality control and metabolic studies.
• Material Science Research: Utilized in the development of specialty polymers and advanced organic materials where controlled functional group manipulation is critical.

Basic Information

Product Name	n-(2-Hydroxybenzoyl)Glycine Bis(Trimethylsilyl) Deriv.
CAS No.	56272-75-4
Molecular Formula	C15H25NO4Si2
Molecular Weight	339.54 g/mol
Synonyms	Bis(trimethylsilyl) Salicylurate; N-(2-Hydroxybenzoyl)glycine Bis(trimethylsilyl) Ester; Salicyluric Acid Bis(trimethylsilyl) Derivative; 2-[(Trimethylsilyloxy)carbonylmethyl]carbamoylphenyl Trimethylsilyl Ether; TMS-Salicylurate; N-(o-Hydroxybenzoyl)glycine Bis(TMS) Deriv.
EINECS	Contact for details

Quality Control

Our n-(2-Hydroxybenzoyl)Glycine Bis(Trimethylsilyl) Deriv. is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.