Description

Glycine Bis(Trimethylsilyl) Deriv. is a key organosilicon derivative of the amino acid glycine, widely used as a versatile protecting group and synthetic intermediate in advanced organic synthesis. Its primary value lies in its ability to mask the amino and carboxyl functionalities, enabling selective reactions and facilitating the synthesis of complex peptides and other sensitive molecules. This high-purity reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable building blocks for sophisticated molecular construction.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly in peptide chemistry.
• Peptide Synthesis: Serves as a protecting agent for glycine residues, preventing unwanted side reactions during solid-phase and solution-phase peptide assembly.
• Agrochemical Research: Used in the development and production of advanced herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Functions as a versatile silylating agent and synthetic intermediate for constructing complex organic molecules in research and development.
• Material Science Precursor: Employed in the surface modification of materials and the synthesis of silicon-containing polymers and hybrid materials.
• Analytical Chemistry: Utilized as a derivatization agent for gas chromatography (GC) and mass spectrometry (MS) to enhance the volatility and detectability of amino acids.

Basic Information

Product Name	Glycine Bis(Trimethylsilyl) Deriv.
CAS No.	56272-62-9
Molecular Formula	C8H21NO2Si2
Molecular Weight	219.43 g/mol
Synonyms	N,O-Bis(trimethylsilyl)glycine; Glycine, N,O-bis(trimethylsilyl)-; Glycine, bis(trimethylsilyl) ester; BSA-Glycine; TMS-Glycine; (Trimethylsilyl)glycine derivative; Glycine TMS derivative; Glycine, N,O-bis[(trimethylsilyl)]-
EINECS	Contact for details

Quality Control

Our Glycine Bis(Trimethylsilyl) Deriv. is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR analysis, to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.