Description

Gluconic Acid, 2,3,5,6-Tetrakis-o-(Trimethylsilyl)-, Lactone is a highly functionalized, silylated derivative of gluconolactone, designed for advanced synthetic applications where precise protection and modification of hydroxyl groups are required. This compound matters for its role as a key protected intermediate and building block in the synthesis of complex molecules, offering enhanced solubility in organic solvents and controlled reactivity. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients, chiral auxiliaries, and novel materials. Its unique structure makes it valuable for applications demanding high purity and specific stereochemistry.

Application

• Pharmaceutical Intermediate: Serves as a protected synthon in the multi-step synthesis of complex drug molecules, particularly those requiring selective deprotection strategies.
• Agrochemical Synthesis: Used as a building block for creating novel, high-performance active ingredients with tailored properties.
• Chiral Pool Reagent: Exploits its inherent chirality for the asymmetric synthesis of enantiomerically pure compounds.
• Polymer & Material Science: Acts as a monomer or functional modifier for creating specialty polymers with unique characteristics.
• Carbohydrate Chemistry: Employed in the synthesis and protection of complex sugars and glycomimetics.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic pathways and methodologies.
• Derivatization Agent: Used in analytical chemistry to enhance the volatility and detectability of polar compounds in techniques like GC-MS.

Basic Information

Product Name	Gluconic Acid, 2,3,5,6-Tetrakis-o-(Trimethylsilyl)-, Lactone
CAS No.	56272-60-7
Molecular Formula	C22H52O7Si4
Molecular Weight	549.0 g/mol (approx.)
Synonyms	2,3,5,6-Tetra-O-(trimethylsilyl)-D-glucono-1,4-lactone; D-Glucono-1,4-lactone 2,3,5,6-tetrakis-O-(trimethylsilyl) ether; Tetrakis-O-(trimethylsilyl)gluconolactone; Per-O-trimethylsilyl gluconolactone; TMS-Gluconolactone; Gluconolactone tetrakis(trimethylsilyl) ether; 56272-60-7; Gluconic acid lactone TMS derivative
EINECS	Contact for details

Quality Control

Our Gluconic Acid, 2,3,5,6-Tetrakis-o-(Trimethylsilyl)-, Lactone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.