Description

n-Acetyl-Dl-Isoleucine Methyl Ester is a chemically modified derivative of the essential amino acid isoleucine, serving as a crucial protected intermediate in advanced organic synthesis. This compound matters for its role in facilitating the controlled construction of complex peptides and other bioactive molecules, where precise functional group manipulation is required. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, peptide synthesis, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in the design and development of new chemical entities for biological screening and lead optimization.
• Peptide Synthesis: Acts as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis protocols.
• Biochemical Research: Employed in studies of amino acid metabolism, enzyme substrates, and protein structure-function relationships.
• Fine Chemical Production: Serves as a precursor for the manufacture of specialized chiral compounds and other high-value fine chemicals.

Basic Information

Product Name	n-Acetyl-Dl-Isoleucine Methyl Ester
CAS No.	56247-42-8
Molecular Formula	C9H17NO3
Molecular Weight	187.24 g/mol
Synonyms	Ac-DL-Ile-OMe; N-Acetyl-DL-isoleucine methyl ester; Methyl N-acetyl-DL-isoleucinate; DL-Isoleucine, N-acetyl-, methyl ester; Methyl 2-(acetylamino)-3-methylpentanoate; 2-(Acetylamino)-3-methylpentanoic acid methyl ester; Acetyl-DL-isoleucine methyl ester; N-Acetylisoleucine methyl ester
EINECS	Contact for details

Quality Control

Our n-Acetyl-Dl-Isoleucine Methyl Ester is produced under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	DL-mixture
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.