Description

(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-Trimethyl-1-Cyclohexen-1-Yl)-2,4,6,8-Nonatetraenoic Acid Trimethylsilyl Ester is a chemically protected derivative of a key retinoid acid intermediate. This compound is valued for its enhanced stability and solubility in organic solvents, making it a crucial building block in advanced synthetic chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of retinoid analogs and Vitamin A derivatives for drug discovery and development.
• Organic Synthesis Building Block: Used in complex multi-step syntheses, including coupling reactions and the construction of polyene systems.
• Agrochemical Research: Serves as an intermediate in the development of new plant growth regulators and bioactive agrochemicals.
• Material Science: Investigated for the synthesis of advanced organic materials with specific optical or electronic properties.
• Biochemical Research: Employed in studies related to cell signaling, differentiation, and the biological pathways of retinoids.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-Trimethyl-1-cyclohexen-1-yl)-2,4,6,8-Nonatetraenoic Acid Trimethylsilyl Ester
CAS No.	56227-27-1
Molecular Formula	C23H38O2Si
Molecular Weight	374.63 g/mol
Synonyms	All-trans-Retinoic Acid Trimethylsilyl Ester; TMS Retinoate; Trimethylsilyl Retinoate; (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid Trimethylsilyl Ester; Tretinoin Trimethylsilyl Ester; Vitamin A Acid TMS Ester; Retinoic Acid TMS Derivative; TMS Ester of Retinoic Acid
EINECS	Contact for details

Quality Control

Our (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-Trimethyl-1-Cyclohexen-1-Yl)-2,4,6,8-Nonatetraenoic Acid Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.