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Methyl 2-(Acetylamino)-4-O,6-o-Bis(Trimethylsilyl)-3-o-Methyl-2-Deoxy-α-D-Galactopyranoside CAS NO 56196-91-9


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CAS No.:56196-91-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 2-(Acetylamino)-4-O,6-o-Bis(Trimethylsilyl)-3-o-Methyl-2-Deoxy-α-D-Galactopyranoside is a sophisticated, protected carbohydrate derivative, specifically a silylated galactopyranoside, designed for advanced synthetic chemistry. This compound is a critical building block for the synthesis of complex oligosaccharides, glycoconjugates, and other bioactive molecules where precise stereochemistry and functional group protection are paramount. It serves as an essential intermediate for researchers and process chemists in pharmaceutical development, particularly in carbohydrate-based drug discovery, vaccine development, and the synthesis of diagnostic reagents.

Application

  • Pharmaceutical Intermediate: A key protected synthon for the synthesis of novel glycosides, glycopeptides, and glycomimetics with potential therapeutic applications.
  • Carbohydrate Chemistry Research: Used in academic and industrial R&D for studying glycosylation reactions, enzymatic transformations, and the assembly of complex carbohydrate structures.
  • Glycoconjugate Synthesis: Serves as a building block for creating glycoproteins, glycolipids, and other conjugates for biological studies and diagnostic assays.
  • Process Chemistry: Employed in the scalable production of carbohydrate-active pharmaceutical ingredients (APIs) where the trimethylsilyl (TMS) protecting groups offer specific reactivity and purification advantages.
  • Chemical Biology Probes: Utilized in the development of labeled sugars and metabolic probes to study cellular processes and glycosylation pathways.

Basic Information

Product Name Methyl 2-(Acetylamino)-4-O,6-o-Bis(Trimethylsilyl)-3-o-Methyl-2-Deoxy-α-D-Galactopyranoside
CAS No. 56196-91-9
Molecular Formula C18H39NO6Si2
Molecular Weight 421.68 g/mol
Synonyms Methyl 2-Acetamido-4,6-O-bis(trimethylsilyl)-3-O-methyl-2-deoxy-α-D-galactopyranoside; Methyl 2-Acetamido-4,6-di-O-trimethylsilyl-3-O-methyl-2-deoxy-α-D-galactopyranoside; 2-Acetamido-4,6-di-O-(trimethylsilyl)-3-O-methyl-2-deoxy-α-D-galactopyranoside methyl glycoside; TMS-protected Methyl N-Acetyl-α-D-galactosaminide derivative; Protected GalNAc derivative; 56196-91-9
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Quality Control

Our Methyl 2-(Acetylamino)-4-O,6-o-Bis(Trimethylsilyl)-3-o-Methyl-2-Deoxy-α-D-Galactopyranoside is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage at 2-8°C.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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