Description

(20S)-3α,17,20,21-Tetrakis[(Trimethylsilyl)Oxy]-5β-Pregnan-11-One CAS NO 56196-46-4 is a high-purity, synthetic steroid derivative characterized by its specific trimethylsilyl (TMS) ether-protected hydroxyl groups. This compound is a critical advanced pharmaceutical intermediate used in the synthesis of complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development and production of specialized therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex corticosteroid and other steroid-based APIs.
• Research & Development: Used in medicinal chemistry for the discovery and structural modification of new steroid-derived drug candidates.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in process development and scale-up for the commercial manufacturing of steroid drugs.
• Biochemical Research: Used as a tool compound to study steroid hormone metabolism and receptor interactions in biochemical assays.

Basic Information

Product Name	(20S)-3α,17,20,21-Tetrakis[(Trimethylsilyl)Oxy]-5β-Pregnan-11-One
CAS No.	56196-46-4
Molecular Formula	C31H60O5Si4
Molecular Weight	625.1 g/mol
Synonyms	5β-Pregnan-11-one, 3α,17,20,21-tetrakis[(trimethylsilyl)oxy]-, (20S)-; (20S)-3α,17α,20,21-Tetrahydroxypregnan-11-one 3,17,20,21-tetrakis-O-(trimethylsilyl) ether; 3α,17α,20,21-Tetrakis(trimethylsiloxy)-5β-pregnan-11-one; 5β-Pregnan-3α,17α,20,21-tetrol 11-one tetra-TMS ether; Tetrakis-O-trimethylsilyl Derivative of (20S)-5β-Pregnan-3α,17α,20,21-tetrol-11-one
EINECS	Contact for details

Quality Control

Our (20S)-3α,17,20,21-Tetrakis[(Trimethylsilyl)Oxy]-5β-Pregnan-11-One is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with full traceability are provided to guarantee batch-to-batch consistency and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.