Description

(2R,3R)-2,3,4-Tris[(Trimethylsilyl)Oxy]Butanal o-Methyl Oxime is a sophisticated, chiral organosilicon-protected intermediate of significant value in synthetic organic chemistry. Its primary importance lies in its role as a key building block for the stereoselective synthesis of complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the fine chemical, agrochemical, and advanced material sectors who require high-purity, enantiomerically pure intermediates for constructing intricate molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of antiviral, antibiotic, and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where specific stereochemistry is crucial for biological activity and environmental safety.
• Fine Chemical Production: Serves as a versatile precursor in the multi-step synthesis of complex natural products, flavors, and fragrances.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and testing of new asymmetric catalytic methodologies.
• Material Science: Potential use in the synthesis of specialized silicon-containing polymers or surface-modifying agents.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis and stereochemistry at universities and corporate research facilities.

Basic Information

Item	Detail
Product Name	(2R,3R)-2,3,4-Tris[(Trimethylsilyl)Oxy]Butanal o-Methyl Oxime
CAS No.	56196-36-2
Molecular Formula	C16H39NO4Si3
Molecular Weight	405.75 g/mol
Synonyms	(2R,3R)-2,3,4-Tris(trimethylsiloxy)butanal O-methyloxime; (2R,3R)-2,3,4-Tris-O-(trimethylsilyl)-D-threose O-methyloxime; D-Threose, 2,3,4-tris-O-(trimethylsilyl)-, O-methyloxime; Butanal, 2,3,4-tris[(trimethylsilyl)oxy]-, O-methyloxime, (2R,3R)-; TMS-protected D-threose O-methyloxime; 56196-36-2
EINECS	Contact for details

Quality Control

Every batch of (2R,3R)-2,3,4-Tris[(Trimethylsilyl)Oxy]Butanal o-Methyl Oxime is produced and tested under strict quality management systems to ensure exceptional purity and stereochemical integrity. Our products undergo rigorous quality testing, including chiral HPLC analysis, to ensure compliance with exacting R&D and production standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.