Description

Propanal, 2,3-Bis[(Trimethylsilyl)Oxy]-, o-Methyloxime, (S)- is a high-purity, chiral synthetic intermediate featuring a protected diol and oxime functional group. This compound is critical for researchers and process chemists requiring precise stereochemistry and moisture-sensitive protecting groups in complex organic syntheses. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials where controlled reactivity and high enantiomeric purity are essential.

Application

• Pharmaceutical Intermediate: A key chiral building block in the multi-step synthesis of complex drug candidates, particularly in segments requiring stereoselective transformations.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where specific stereoisomers exhibit enhanced biological activity.
• Advanced Material Precursor: Serves as a specialized monomer or linker in the synthesis of functionalized polymers and dendrimers with tailored properties.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and screening of new chiral catalysts.
• Natural Product Synthesis: Facilitates the construction of complex natural product skeletons, leveraging its protected functionalities for sequential reactions.
• Process Chemistry & Scale-up: Provides a reliable, high-quality intermediate for optimizing and scaling synthetic routes from laboratory to pilot plant.

Basic Information

Product Name	Propanal, 2,3-Bis[(Trimethylsilyl)Oxy]-, o-Methyloxime, (S)-
CAS No.	56196-02-2
Molecular Formula	C12H29NO3Si2
Molecular Weight	291.53 g/mol
Synonyms	(S)-2,3-Bis(trimethylsilyloxy)propanal O-Methyloxime; (S)-Propanal, 2,3-bis[(trimethylsilyl)oxy]-, O-methyloxime; (2S)-2,3-Bis(trimethylsilyloxy)propanal methyloxime; (S)-2,3-Bis-O-(trimethylsilyl)glyceraldehyde methyloxime; (S)-Glyceraldehyde Acetonide TMS Derivative Methyloxime; TMS-protected (S)-Glyceraldehyde Oxime; Chiral TMS-Glyceraldehyde Oxime Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Propanal, 2,3-Bis[(Trimethylsilyl)Oxy]-, o-Methyloxime, (S)- is characterized using advanced analytical techniques including NMR, HPLC, and GC to confirm identity, chemical purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opened to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.