Description

(5α,12β,19α,20R)-20-Acetyloxy-2,3-Didehydroaspidospermidine-3-Carboxylic Acid Methyl Ester is a high-purity, complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and intermediate for the development of novel bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex natural products and potential therapeutic agents.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of complex indole alkaloids and potential drug candidates.
• Organic Synthesis Research: Valuable building block for methodological studies in stereoselective synthesis and total synthesis projects.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to explore new biological activities derived from the aspidosperma skeleton.
• Reference Standard: Serves as an analytical standard for quality control and identification in related chemical processes.
• Academic Research: Employed in university and institutional labs for studying alkaloid chemistry and biosynthesis pathways.
• Fine Chemical Production: Intermediate for the manufacture of specialized, high-value chemicals for research and development.

Basic Information

Product Name	(5α,12β,19α,20R)-20-Acetyloxy-2,3-Didehydroaspidospermidine-3-Carboxylic Acid Methyl Ester
CAS No.	56143-41-0
Molecular Formula	C23H28N2O4
Molecular Weight	396.48 g/mol
Synonyms	Methyl (5α,12β,19α,20R)-20-(acetyloxy)-2,3-didehydroaspidospermidine-3-carboxylate; 20-Acetoxy-2,3-didehydroaspidospermidine-3-carboxylic acid methyl ester; Aspidospermidine derivative; 3-Carbomethoxy-20-acetoxy-2,3-didehydroaspidospermidine; Tabersonine derivative
EINECS	Contact for details

Quality Control

Our (5α,12β,19α,20R)-20-Acetyloxy-2,3-Didehydroaspidospermidine-3-Carboxylic Acid Methyl Ester is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, essential for research and synthesis applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP standards for advanced intermediates and provide full traceability documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.