Description

(2R,3R)-2,3-Bis[(2,2,2-Trifluoroacetyl)Oxy]Butanedioic Acid Dibutyl Ester is a high-purity chiral building block and derivatization agent, valued for its role in introducing trifluoroacetyl-protected diol functionalities. This compound is critical for ensuring precise stereochemistry and reactivity in advanced synthetic pathways. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis, chiral resolution, and the development of active pharmaceutical ingredients (APIs).

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key building block for constructing complex molecules with defined stereocenters, essential for API development.
• Derivatization Agent for Analytical Chemistry: Used to modify chiral compounds for enhanced separation and detection in chromatographic methods like HPLC and GC.
• Asymmetric Catalyst and Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands and organocatalysts.
• Fine Chemical and Specialty Material Production: Employed in the research and scale-up of high-value specialty chemicals requiring specific diol protection strategies.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(2R,3R)-2,3-Bis[(2,2,2-Trifluoroacetyl)Oxy]Butanedioic Acid Dibutyl Ester
CAS No.	56114-67-1
Molecular Formula	C16H20F6O8
Molecular Weight	454.32 g/mol
Synonyms	Dibutyl (2R,3R)-2,3-bis(2,2,2-trifluoroacetoxy)succinate; (R,R)-Dibutyl O,O'-(2,2,2-Trifluoroacetyl)tartrate; L-(+)-Dibutyl Tartrate Bis(trifluoroacetate); (2R,3R)-Dibutyl 2,3-bis(trifluoroacetoxy)succinate; Butanedioic acid, 2,3-bis[(2,2,2-trifluoroacetyl)oxy]-, dibutyl ester, (2R,3R)-; (2R,3R)-Tartaric Acid Dibutyl Ester Bis(trifluoroacetate)
EINECS	Contact for details

Quality Control

Our (2R,3R)-2,3-Bis[(2,2,2-Trifluoroacetyl)Oxy]Butanedioic Acid Dibutyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.