Description

N,n-Bis(Trimethylsilyl)-1-Acetyl-5-[(Trimethylsilyl)Oxy]-1H-Indole-3-Ethanamine is a sophisticated, multi-functional silylated indole derivative designed for advanced synthetic chemistry. This compound matters as a key protected intermediate, offering enhanced stability and solubility for complex organic transformations, particularly in sensitive reaction environments. Pharmaceutical and agrochemical R&D laboratories need it for the synthesis of novel active ingredients, where its protective groups facilitate precise molecular construction.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex drug candidates, particularly those with indole-based core structures.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its functionalized indole scaffold.
• Advanced Material Synthesis: Serves as a precursor for creating specialized organic molecules used in materials science, such as organic semiconductors or ligands for catalysis.
• Protecting Group Chemistry: The trimethylsilyl (TMS) groups act as protective agents for amine and hydroxyl functionalities during complex synthetic sequences.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of fine chemicals and active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry at universities and research institutes.

Basic Information

Product Name	N,n-Bis(Trimethylsilyl)-1-Acetyl-5-[(Trimethylsilyl)Oxy]-1H-Indole-3-Ethanamine
CAS No.	56114-61-5
Molecular Formula	C22H42N2O2Si3
Molecular Weight	466.86 g/mol
Synonyms	1H-Indole-3-ethanamine, N,N-bis(trimethylsilyl)-1-acetyl-5-[(trimethylsilyl)oxy]-; 1-Acetyl-5-(trimethylsiloxy)-N,N-bis(trimethylsilyl)tryptamine; 5-(Trimethylsiloxy)-1-acetyl-N,N-bis(trimethylsilyl)tryptamine; Tryptamine derivative, silylated; N,N-Bis(trimethylsilyl)-1-acetyl-5-(trimethylsiloxy)tryptamine; 5-Hydroxy-1-acetyltryptamine, tris(trimethylsilyl) derivative; Protected 5-hydroxytryptamine derivative
EINECS	Contact for details

Quality Control

Our N,n-Bis(Trimethylsilyl)-1-Acetyl-5-[(Trimethylsilyl)Oxy]-1H-Indole-3-Ethanamine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to prevent decomposition. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.