Description

2-O,3-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-D-Altrose is a fully protected derivative of the rare sugar D-altrose, where all hydroxyl groups are silylated with trimethylsilyl (TMS) groups. This modification is critical for its primary role as a versatile and stable synthetic intermediate in advanced organic and carbohydrate chemistry. It is particularly valuable for researchers and manufacturers in the pharmaceutical and fine chemical industries who require protected sugar building blocks for the synthesis of complex molecules, nucleosides, and glycoconjugates.

Application

• Pharmaceutical Intermediate: Serves as a key protected building block in the multi-step synthesis of novel drug candidates, particularly in antiviral and anticancer research.
• Carbohydrate Chemistry Research: Used in academic and industrial R&D for studying glycosylation reactions and synthesizing complex oligosaccharides with precise stereochemistry.
• Glycoconjugate Synthesis: Acts as a precursor for creating glycopeptides, glycolipids, and other biologically active conjugates where the sugar moiety needs to be selectively deprotected.
• Chiral Pool Starting Material: Provides a source of chirality for the asymmetric synthesis of non-carbohydrate natural products and specialty chemicals.
• Process Development: Employed in scaling up synthetic routes that require a stable, moisture-protected form of D-altrose to ensure reproducibility and yield.

Basic Information

Product Name	2-O,3-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-D-Altrose
CAS No.	56114-56-8
Molecular Formula	C24H58O6Si5
Molecular Weight	603.18 g/mol
Synonyms	D-Altrose, pentakis(trimethylsilyl) ether; Pentakis-O-(trimethylsilyl)-D-altrose; 1,2,3,4,5,6-Penta-O-trimethylsilyl-D-altrose; Altrose pentatrimethylsilyl ether; TMS-Altrose (fully protected); D-Altropyranose, pentakis-O-(trimethylsilyl)-; 56114-56-8; Fully silylated D-altrose
EINECS	Contact for details

Quality Control

Every batch of 2-O,3-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-D-Altrose is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC/HPLC)	≥ 90.0% (Total isomers)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.