Description

4,5,6,7-Tetrahydrospiro[Benzofuran-3(2H),1'-Cyclohexane]-2',4',6'-Trione is a high-purity, complex spirocyclic organic compound with significant synthetic utility. This specialized chemical serves as a critical advanced intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by pharmaceutical R&D and custom synthesis organizations for constructing intricate molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those requiring spirocyclic or fused ring systems.
• Organic Synthesis Research: Used in academic and industrial laboratories for developing new synthetic methodologies and exploring novel chemical spaces.
• Agrochemical Development: Serves as a precursor for creating new active ingredients with potential herbicidal or pesticidal activity.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.

Basic Information

Product Name	4,5,6,7-Tetrahydrospiro[Benzofuran-3(2H),1'-Cyclohexane]-2',4',6'-Trione
CAS No.	56114-43-3
Molecular Formula	C14H16O4
Molecular Weight	248.27 g/mol
Synonyms	1,3,5-Cyclohexanetrione, 2,3,4,5-tetrahydrospiro[benzofuran-3,1'-cyclohexane]-2',4',6'-trione; Spiro[benzofuran-3(2H),1'-cyclohexane]-2',4',6'-trone, 4,5,6,7-tetrahydro-; 4,5,6,7-Tetrahydrospiro[benzofuran-3(2H),1'-cyclohexane]-2',4',6'-trione; 2,3,4,5-Tetrahydrospiro[benzofuran-3,1'-cyclohexane]-2',4',6'-trione; Spirocyclic Benzofuran Trione Derivative
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrahydrospiro[Benzofuran-3(2H),1'-Cyclohexane]-2',4',6'-Trione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.