Description

L-Atabrine Dihydrochloride is a high-purity, dihydrochloride salt form of the quinacrine derivative, known for its specific biological activity. This compound is critical for research and development applications requiring a well-characterized, stable reference standard. It is primarily utilized by pharmaceutical research laboratories, academic institutions, and biotechnology companies engaged in pharmacological studies and analytical method development.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method validation in drug development.
• Biochemical Research: Used as a key reagent in studies investigating antimalarial mechanisms, enzyme interactions, and cellular processes.
• Academic & Institutional Research: Employed in university and government laboratories for fundamental pharmacological and chemical research.
• Analytical Chemistry: Acts as a high-purity standard for calibration in techniques like HPLC, LC-MS, and spectrophotometry.
• Preclinical Studies: Utilized in in-vitro and in-vivo research models to evaluate biological activity and pharmacokinetics.

Basic Information

Product Name	L-Atabrine Dihydrochloride
CAS No.	56100-42-6
Molecular Formula	C23H30ClN3O·2HCl
Molecular Weight	472.88 g/mol
Synonyms	Quinacrine Dihydrochloride; Mepacrine Dihydrochloride; Atebrin Dihydrochloride; SN 390 Dihydrochloride; 6-Chloro-9-(4-diethylamino-1-methylbutyl)amino-2-methoxyacridine Dihydrochloride; Acrichine Dihydrochloride; (RS)-N'-(6-Chloro-2-methoxyacridin-9-yl)-N,N-diethylpentane-1,4-diamine Dihydrochloride
EINECS	Contact for details

Quality Control

Our L-Atabrine Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines for reference standards to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.