Description

Estra-1,3,5,7,9-Pentaene-3,17-Diol, 3-(Hydrogen Sulfate), Monosodium Salt, (17Alpha)- is a high-purity, conjugated estrogen derivative with a specific sulfated structure. This compound is critical for pharmaceutical research and development, particularly in the study of hormone receptor interactions and metabolic pathways. It serves as a key intermediate or reference standard for manufacturers and research institutions in the steroid and endocrinology fields, enabling the synthesis and analysis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of estrogen-related compounds via HPLC, LC-MS, or other chromatographic techniques.
• Biochemical Research: Applied in in vitro studies to investigate estrogen receptor (ER) binding affinity, selectivity, and downstream signaling mechanisms.
• Metabolite Studies: Utilized as a standard or tracer in research focused on the metabolism and sulfation pathways of natural and synthetic estrogens.
• Academic & Discovery Research: Provides a foundational chemical entity for universities and biotech companies exploring new targets in endocrinology and women's health.

Basic Information

Item	Detail
Product Name	Estra-1,3,5,7,9-Pentaene-3,17-Diol, 3-(Hydrogen Sulfate), Monosodium Salt, (17Alpha)-
CAS No.	56086-66-9
Molecular Formula	C18H21NaO6S
Molecular Weight	388.41 g/mol
Synonyms	Equilin Sodium Sulfate; Sodium Equilin Sulfate; 17α-Equilin Sodium Sulfate; 3-Sulfooxyestra-1,3,5,7,9-pentaen-17-ol Monosodium Salt; (17α)-Estra-1,3,5,7,9-pentaene-3,17-diol 3-(Hydrogen Sulfate) Monosodium Salt; Equilin 3-Sulfate Sodium Salt; NSC 147834
EINECS	Contact for details

Quality Control

Our production of Estra-1,3,5,7,9-Pentaene-3,17-Diol, 3-(Hydrogen Sulfate), Monosodium Salt, (17Alpha)- adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and related substances. Certificates of Analysis (COA) documenting all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment. For long-term storage, consider desiccants to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Assay (on dried basis)	97.0% - 103.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.