Description

Phosphonic Acid, [3-[(Trimethylsilyl)Amino]Propyl]-, Bis(Trimethylsilyl) Ester is a specialized organosilicon compound featuring both phosphonic acid ester and silylamine functional groups. This unique bifunctional structure makes it a valuable silylating agent and reactive intermediate in advanced organic synthesis and materials science. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for surface modification, coupling reactions, and the synthesis of novel silicon-containing molecules.

Application

• Silylating Agent: Used to introduce trimethylsilyl (TMS) protecting groups onto sensitive functional groups like amines and hydroxyls in complex organic synthesis.
• Surface Modification: Acts as a coupling agent or primer for modifying the surface properties of inorganic materials like silica, glass, and metals to improve adhesion or impart specific functionalities.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly those requiring silicon or phosphonate moieties.
• Polymer & Resin Additive: Incorporated as a cross-linking agent or modifier in silicone resins and specialty polymers to enhance thermal stability, adhesion, or chemical resistance.
• Agrochemical Synthesis: Utilized in the production of novel herbicides, fungicides, or plant growth regulators that contain organophosphorus or silane components.
• Catalyst & Ligand Precursor: Employed in the preparation of metal-organic catalysts and ligands for homogeneous catalysis.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and material properties.

Basic Information

Product Name	Phosphonic Acid, [3-[(Trimethylsilyl)Amino]Propyl]-, Bis(Trimethylsilyl) Ester
CAS No.	56051-92-4
Molecular Formula	C12H34NO3PSi3
Molecular Weight	355.64 g/mol
Synonyms	Bis(trimethylsilyl) [3-(trimethylsilylamino)propyl]phosphonate; [3-(Trimethylsilylamino)propyl]phosphonic Acid Bis(trimethylsilyl) Ester; N-(3-Phosphonatopropyl)-N-(trimethylsilyl)aminotris(trimethylsilanolate) (P,P'); (3-((Trimethylsilyl)amino)propyl)phosphonic Acid Bis(trimethylsilyl) Ester; ATMS Phosphonate; Amino-propyl Phosphonate Silyl Ester
EINECS	Contact for details

Quality Control

Every batch of Phosphonic Acid, [3-[(Trimethylsilyl)Amino]Propyl]-, Bis(Trimethylsilyl) Ester is produced and tested under strict quality management protocols. We ensure high purity and consistent performance through comprehensive analytical methods including NMR, GC, and HPLC. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformity to agreed specifications. Our quality system supports cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and may degrade upon exposure to strong bases. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~0.92 g/mL
Refractive Index (n20D)	~1.430

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.