Description

Bis(Trimethylsilyl) 2-[(Trimethylsilyl)Amino]Ethylphosphonate is a specialized organosilicon reagent featuring a unique phosphonate ester and silylated amine functionality. This compound is valued for its role as a key intermediate and protecting group reagent in advanced synthetic chemistry, particularly for modifying sensitive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require precise control over molecular structure and reactivity. The compound is supplied with a high level of purity to ensure consistent performance in demanding applications.

Application

• Pharmaceutical Intermediate: Used in the synthesis of complex drug candidates, particularly those containing phosphonate or amino acid analogs.
• Peptide & Nucleotide Chemistry: Serves as a protecting group for phosphate and amine functionalities during solid-phase and solution-phase synthesis.
• Agrochemical Synthesis: A key building block for creating novel herbicides, insecticides, and plant growth regulators with enhanced properties.
• Material Science Precursor: Employed in the development of silicon-based polymers, coatings, and surface-modifying agents.
• Cross-Coupling Reagents: Acts as a reagent in metal-catalyzed cross-coupling reactions to form carbon-phosphorus bonds.
• Chemical Derivatization: Used to silylate sensitive compounds for analysis by gas chromatography (GC) or mass spectrometry (MS).
• Ligand Synthesis: A precursor for creating specialized ligands used in catalysis and coordination chemistry.

Basic Information

Item	Detail
Product Name	Bis(Trimethylsilyl) 2-[(Trimethylsilyl)Amino]Ethylphosphonate
CAS No.	56051-90-2
Molecular Formula	C11H30NO3PSi3
Molecular Weight	327.59 g/mol
Synonyms	2-[(Trimethylsilyl)amino]ethylphosphonic acid bis(trimethylsilyl) ester; N-(Trimethylsilyl)-2-aminoethylphosphonic acid bis(trimethylsilyl) ester; Tris(trimethylsilyl) 2-aminoethylphosphonate; ATEP; (2-((Trimethylsilyl)amino)ethyl)phosphonic acid bis(trimethylsilyl) ester; O,O-Bis(trimethylsilyl) 2-[(trimethylsilyl)amino]ethylphosphonate; N,O,O-Tris(trimethylsilyl)-2-aminoethylphosphonamide
EINECS	Contact for details

Quality Control

Our Bis(Trimethylsilyl) 2-[(Trimethylsilyl)Amino]Ethylphosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC or HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.