Description

2-[[[(Trimethylsilyl)Amino]Carbonyl]Amino]Butanedioic Acid Dimethyl Ester is a specialized organosilicon-protected amino acid derivative, serving as a key synthetic intermediate. Its value lies in providing a protected amino functionality that is stable under various reaction conditions, enabling precise and efficient multi-step organic synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing peptide mimetics, active pharmaceutical ingredients (APIs), and other high-value nitrogen-containing compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, especially for peptide-based therapeutics and enzyme inhibitors.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis as a protected aspartic acid or glutamic acid derivative, facilitating complex peptide chain assembly.
• Organic Synthesis Reagent: Acts as a versatile synthon for introducing protected amino and carboxylic ester groups into complex molecular architectures.
• Agrochemical Research: Employed in the development of advanced pesticides and herbicides that require specific amino acid-like structures for bioactivity.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers and dendrimers with tailored properties.
• Bioconjugation Chemistry: Useful for creating linkers and spacers in antibody-drug conjugates (ADCs) and other bioconjugation applications.

Basic Information

Product Name	2-[[[(Trimethylsilyl)Amino]Carbonyl]Amino]Butanedioic Acid Dimethyl Ester
CAS No.	56051-84-4
Molecular Formula	C11H22N2O5Si
Molecular Weight	290.39 g/mol
Synonyms	Dimethyl 2-[[[(trimethylsilyl)amino]carbonyl]amino]butanedioate; N-[(Trimethylsilyl)carbamoyl]aspartic Acid Dimethyl Ester; Aspartic Acid, N-[(trimethylsilyl)carbamoyl]-, Dimethyl Ester; TMS-Carbamoyl-Aspartic Acid Dimethyl Ester; (TMS-NHCO)-Asp(OMe)-OMe; NSC 339063; Dimethyl (2S)-2-({[(trimethylsilyl)amino]carbonyl}amino)butanedioate (for enantiopure form)
EINECS	Contact for details

Quality Control

Our production of 2-[[[(Trimethylsilyl)Amino]Carbonyl]Amino]Butanedioic Acid Dimethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.