Description

4,5-Dihydro-4,4-Dimethyl-3-(Trimethylsiloxy)-2(3H)-Furanone CAS NO 56051-80-0 is a specialized organosilicon compound featuring a protected lactone functionality. This chemical matters as a versatile building block and reagent in advanced organic synthesis, offering unique reactivity for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications such as asymmetric synthesis and the preparation of silicon-containing intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon or protecting group reagent in the synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Advanced Material Precursor: Acts as a monomer or modifying agent in the production of specialty silicones and performance polymers.
• Asymmetric Catalysis: Employed as a substrate or auxiliary in catalytic reactions to induce chirality in target molecules.
• Organic Synthesis Reagent: Functions as a trimethylsilyl enol ether equivalent for aldol and related carbon-carbon bond-forming reactions.
• Flavor & Fragrance Chemistry: Utilized in the synthesis of complex lactone and ester compounds for high-value aroma chemicals.

Basic Information

Product Name	4,5-Dihydro-4,4-Dimethyl-3-(Trimethylsiloxy)-2(3H)-Furanone
CAS No.	56051-80-0
Molecular Formula	C9H18O3Si
Molecular Weight	202.32 g/mol
Synonyms	3-(Trimethylsiloxy)-4,5-dihydro-4,4-dimethylfuran-2(3H)-one; 4,4-Dimethyl-3-trimethylsiloxy-dihydrofuran-2-one; 4,5-Dihydro-4,4-dimethyl-3-(trimethylsilyloxy)-2(3H)-furanone; TMS enol ether of 4,4-dimethyl-2-oxotetrahydrofuran; Trimethylsilyl 4,4-dimethyl-2-oxo-3-tetrahydrofuranyl ether; 3-Trimethylsilyloxy-4,4-dimethyldihydrofuran-2-one
EINECS	Contact for details

Quality Control

Our 4,5-Dihydro-4,4-Dimethyl-3-(Trimethylsiloxy)-2(3H)-Furanone undergoes rigorous quality testing to ensure compliance with industry standards for research and process chemistry. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as fluorides and strong alkalis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.