Description

Estra-1,3,5(10)-Triene-3,17-Diol, 3-(Hydrogen Sulfate), Monosodium Salt, (17Alpha)- is a high-purity, water-soluble sodium sulfate ester derivative of estradiol. This compound is a critical pharmaceutical intermediate, valued for its role in the synthesis of advanced steroidal APIs and prodrugs. It is primarily utilized by pharmaceutical manufacturers and advanced research institutions in the development and production of hormone-based therapies and diagnostic agents. Our product is supplied with rigorous quality control to ensure batch-to-batch consistency and reliability for your most demanding applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of steroidal active pharmaceutical ingredients (APIs), particularly estrogen analogs and conjugates.
• Prodrug Development: Used in research and production of prodrugs designed for improved bioavailability and targeted delivery of estradiol.
• Hormone Replacement Therapy (HRT): Serves as a precursor in the manufacture of specific formulations for HRT and other endocrine disorder treatments.
• Biochemical Research: Employed as a standard or reagent in steroidal metabolism studies, receptor binding assays, and enzymatic studies.
• Diagnostic Agent Synthesis: Intermediate in the production of labeled compounds or conjugates for diagnostic kits and assays.
• Veterinary Pharmaceuticals: Used in the development of hormonal treatments for animals.

Basic Information

Product Name	Estra-1,3,5(10)-Triene-3,17-Diol, 3-(Hydrogen Sulfate), Monosodium Salt, (17Alpha)-
CAS No.	56050-04-5
Molecular Formula	C18H23NaO5S
Molecular Weight	374.42 g/mol
Synonyms	Estradiol 3-Sulfate Sodium Salt; 17α-Estradiol 3-Sulfate Sodium Salt; Sodium Estradiol Sulfate; Estr-5(10)-en-3,17-diol, 3-(hydrogen sulfate), monosodium salt, (17α)-; 17α-Estradiol 3-Monosulfate Sodium Salt; Estra-1,3,5(10)-trien-17α-ol-3-yl Sulfate Sodium Salt; NSC 147834
EINECS	Contact for details

Quality Control

Our Estra-1,3,5(10)-Triene-3,17-Diol, 3-(Hydrogen Sulfate), Monosodium Salt, (17Alpha)- is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) documenting all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.